Regulation of gene transcription by the oncoprotein MYC.

  title={Regulation of gene transcription by the oncoprotein MYC.},
  author={Bernhard L{\"u}scher and J{\"o}rg Vervoorts},
  volume={494 2},
The proteins of the MYC/MAX/MAD network are central regulators of many key processes associated with basic cell physiology. These include the regulation of protein biosynthesis, energy metabolism, proliferation, and apoptosis. Molecularly the MYC/MAX/MAD network achieves these broad activities by controlling the expression of many target genes, which are primarily responsible for the diverse physiological consequences elicited by the network. The MYC proteins of the network possess oncogenic… CONTINUE READING


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