Regulation of gene expression and cell function by extracellular matrix.

@article{Jones1993RegulationOG,
  title={Regulation of gene expression and cell function by extracellular matrix.},
  author={Parmecia L. Jones and Christian Schmidhauser and Mina J. Bissell},
  journal={Critical reviews in eukaryotic gene expression},
  year={1993},
  volume={3 2},
  pages={
          137-54
        }
}
Cells within tissues of multicellular organisms are intimately surrounded by a complex arrangement of extracellular proteins that together act as an informational entity in the sense that they receive, impart, and integrate structural and functional signals. This macromolecular network, composed largely of glycoproteins and proteoglycans, is collectively known as the extracellular matrix (ECM). In this review we aim to show that the ECM plays a fundamental role in both the control of gene… CONTINUE READING

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