Regulation of gap junctions by protein phosphorylation.

  title={Regulation of gap junctions by protein phosphorylation.},
  author={Juan C S{\'a}ez and Agust{\'i}n D Mart{\'i}nez and Mar{\'i}a C Bra{\~n}es and Hern{\'a}n Gonz{\'a}lez},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={31 5},
Gap junctions are constituted by intercellular channels and provide a pathway for transfer of ions and small molecules between adjacent cells of most tissues. The degree of intercellular coupling mediated by gap junctions depends on the number of gap junction channels and their activity may be a function of the state of phosphorylation of connexins, the structural subunit of gap junction channels. Protein phosphorylation has been proposed to control intercellular gap junctional communication at… CONTINUE READING