Regulation of galectin-9 expression and release in Jurkat T cell line cells.

@article{Chabot2002RegulationOG,
  title={Regulation of galectin-9 expression and release in Jurkat T cell line cells.},
  author={Sophie Chabot and Yumiko Kashio and Masako Seki and Yukako Shirato and Kazuhiro Nakamura and Nozomu Nishi and Takanori Nakamura and Ryoji Matsumoto and Mitsuomi Hirashima},
  journal={Glycobiology},
  year={2002},
  volume={12 2},
  pages={111-8}
}
Ecalectin/galectin-9 was recently described as a novel eosinophil chemoattractant highly expressed in immune tissues. We investigated the regulation of galectin-9 expression and release in Jurkat (a T cell line) cells. We demonstrated that medium and long-sized galectin-9 isoforms were constitutively expressed, and phorbol 12-myriastate 13-acetate (PMA) upregulated the level of galectin-9 mRNA in Jurkat cells. Western blotting and flow cytometry analyses revealed that PMA stimulation resulted… CONTINUE READING