Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State
- Fianne L. P. Sips, Elin Nyman, +5 authors Zane B Andrews
- PloS one
- 2015
Highly Influenced
5 Excerpts
Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification.
@article{Campbell1992RegulationOF,
title={Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification.},
author={Peter J. Campbell and Michael Carlson and James O Hill and N. Nurjhan},
journal={The American journal of physiology},
year={1992},
volume={263 6 Pt 1},
pages={E1063-9}
}- Published 1992 in The American journal of physiology
The regulation of lipolysis, free fatty acid appearance into plasma (FFA R(a)), an FFA reesterification and oxidation were examined in seven healthy humans infused intravenously with insulin at rates of 4, 8, 25, and 400 mU.m-2.min-1. Glycerol and FFA R(a) were determined by isotope dilution methods, and FFA oxidation was calculated by indirect calorimetry or by measurement of expired 14CO2 from infused [1-14C]palmitate. These measurements were used to calculate total FFA reesterification… CONTINUE READING