Regulation of firing of dopaminergic neurons and control of goal-directed behaviors

@article{Grace2007RegulationOF,
  title={Regulation of firing of dopaminergic neurons and control of goal-directed behaviors},
  author={Anthony A. Grace and Stan B Floresco and Yukiori Goto and Daniel J Lodge},
  journal={Trends in Neurosciences},
  year={2007},
  volume={30},
  pages={220-227}
}
There are several brain regions that have been implicated in the control of motivated behavior and whose disruption leads to the pathophysiology observed in major psychiatric disorders. These systems include the ventral hippocampus, which is involved in context and focus on tasks, the amygdala, which mediates emotional behavior, and the prefrontal cortex, which modulates activity throughout the limbic system to enable behavioral flexibility. Each of these systems has overlapping projections to… CONTINUE READING

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