Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex.

Abstract

The invasion of migratory cells through connective tissues involves metallo- and serine types of cell surface proteases. We show that formation of a novel protease complex, consisting of the membrane-bound prolyl peptidases seprase and dipeptidyl peptidase IV (DPPIV), at invadopodia of migratory fibroblasts is a prerequisite for cell invasion and migration… (More)

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Cite this paper

@article{Ghersi2002RegulationOF, title={Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex.}, author={Giulio Ghersi and Huan Dong and Leslie A. Goldstein and Yunyun Yeh and Lari Hakkinen and Hannu S Larjava and Wen-Tien Chen}, journal={The Journal of biological chemistry}, year={2002}, volume={277 32}, pages={29231-41} }