Regulation of fatty acid movement in human adipose tissue in the postabsorptive-to-postprandial transition.

@article{Frayn1994RegulationOF,
  title={Regulation of fatty acid movement in human adipose tissue in the postabsorptive-to-postprandial transition.},
  author={Keith N. Frayn and Samyah Shadid and R Hamlani and Sandy M. Humphreys and Miss Victoria L Clark and Barbara A. Fielding and O M Boland and Simon W. Coppack},
  journal={The American journal of physiology},
  year={1994},
  volume={266 3 Pt 1},
  pages={
          E308-17
        }
}
There is net outward flow of fatty acids from adipose tissue in the fasted state but net inward flow and storage in the postprandial state. We investigated how this is regulated. Arteriovenous differences were measured across a subcutaneous adipose depot in six normal subjects before and for 5 h after a meal containing 80 g fat and 80 g carbohydrate. In five further experiments, insulin was infused at 40 mU.m-2.min-1 from 30 min after the meal, clamping the plasma glucose. Net transcapillary… CONTINUE READING
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