Regulation of expression of microRNAs by DNA methylation in lung cancer.

@article{Singh2016RegulationOE,
  title={Regulation of expression of microRNAs by DNA methylation in lung cancer.},
  author={Dhirendra Kumar Singh and Sudeep K. Bose and Sachin Kumar},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2016},
  volume={21 7},
  pages={589-99}
}
Differential expression of miRNAs has been linked with lung carcinogenesis. Recent studies have indicated that DNA hypermethylation can lead to silencing of tumor suppressor miRNA-encoding genes. Restoration of tumor suppressor miRNAs using inhibitors of DNA methyltransferases has been shown to suppress cell proliferation, angiogenesis, invasion and… CONTINUE READING