Regulation of expression of Streptococcus mutans genes important to virulence.

@article{Hudson1990RegulationOE,
  title={Regulation of expression of Streptococcus mutans genes important to virulence.},
  author={Michael C. Hudson and Roy Curtiss},
  journal={Infection and immunity},
  year={1990},
  volume={58 2},
  pages={464-70}
}
Studies were initiated to investigate the regulation of Streptococcus mutans genes which are believed to be important to virulence. Operon fusions were constructed between S. mutans gene regulatory regions and a promoterless chloramphenicol acetyltransferase gene (cat) found on the plasmid pMH109. Specifically, fusions were generated between cat and the S. mutans genes encoding fructosyltransferase (ftf) and the glucosyltransferase B/C (gtfB/C) operon. Constructs were confirmed by restriction… CONTINUE READING

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