Regulation of enterokinase synthesis in animal and human small intestine by luminal signals: its implication in upper gastrointestinal surgery.

@article{Bett1979RegulationOE,
  title={Regulation of enterokinase synthesis in animal and human small intestine by luminal signals: its implication in upper gastrointestinal surgery.},
  author={N J Bett},
  journal={The British journal of surgery},
  year={1979},
  volume={66 10},
  pages={
          708-11
        }
}
  • N J Bett
  • Published 1979 in The British journal of surgery
Enterokinase is an enzyme produced by the mucosa of the small intestine. Its sole function is to activate trypsinogen to trypsin. In animals and man the duodenum and proximal jejunum have high levels of activity whereas the remaining small bowel has minimal levels. A reproducible assay was developed for measuring mucosal enterokinase activity applicable to operative and endoscopic biopsies. Anaesthetic and operative techniques were developed for small intestinal resections in guinea-pigs to… CONTINUE READING