Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex.

Abstract

Endosomes and endosomal vesicles (EVs) rapidly move along cytoskeletal filaments allowing them to exchange proteins and lipids between different endosomal compartments, lysosomes, the trans-Golgi network (TGN), and the plasma membrane. The precise mechanisms that connect membrane traffic between the TGN and perinuclear endosomal compartments with motor… (More)
DOI: 10.1073/pnas.0904268106

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