Regulation of development in the fully grown mouse oocyte: chromosome-mediated temporal and spatial differentiation of the cytoplasm and plasma membrane.

Abstract

The relationship between nuclear maturation and the differentiation of the cytoplasm and plasma membrane during resumption of arrested meiosis was investigated by culture of GV-and MII-stage mouse oocytes in the presence and absence of nocodazole. Culture in the presence of nocodazole was associated with dispersal of MI and MII chromosomes throughout the… (More)

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