Regulation of dendrite morphology and excitatory synapse formation by zDHHC15

  title={Regulation of dendrite morphology and excitatory synapse formation by zDHHC15},
  author={Bhavin S Shah and J. Shimell and S. Bamji},
  journal={Journal of Cell Science},
  • Bhavin S Shah, J. Shimell, S. Bamji
  • Published 2019
  • Medicine, Biology
  • Journal of Cell Science
  • ABSTRACT Protein palmitoylation is the most common post-translational lipid modification in the brain and is mediated by a family of 24 zDHHC enzymes. There has been growing interest in zDHHCs due to mounting evidence that these enzymes play key roles in the development and function of neuronal connections, and the fact that a number of zDHHCs have been associated with neurodevelopmental and neurodegenerative diseases. Loss-of-function variants in several zDHHCs, including zDHHC15, have been… CONTINUE READING
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