Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation.

@article{Cai1998RegulationOC,
  title={Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation.},
  author={Shuang Cai and Lidija Pestic-Dragovich and Martha E. O'Donnell and Ning Wang and Donald E. Ingber and Elliot L. Elson and Primal de Lanerolle},
  journal={The American journal of physiology},
  year={1998},
  volume={275 5 Pt 1},
  pages={C1349-56}
}
The role of myosin light chain phosphorylation in regulating the mechanical properties of the cytoskeleton was studied in NIH/3T3 fibroblasts expressing a truncated, constitutively active form of smooth muscle myosin light chain kinase (tMK). Cytoskeletal stiffness determined by quantifying the force required to indent the apical surface of adherent cells… CONTINUE READING