Regulation of components of the brain and cardiac renin-angiotensin systems by 17beta-estradiol after myocardial infarction in female rats.

@article{Dean2006RegulationOC,
  title={Regulation of components of the brain and cardiac renin-angiotensin systems by 17beta-estradiol after myocardial infarction in female rats.},
  author={Stephanie A. Dean and Junhui Tan and Roselyn A White and Edward R O'brien and Frans H H Leenen},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2006},
  volume={291 1},
  pages={R155-62}
}
The present study tested the hypothesis that 17beta-estradiol (E2) inhibits increases in angiotensin-converting enzyme (ACE) and ANG II type 1 receptor (AT1R) in the brain and heart after myocardial infarction (MI) and, thereby, inhibits development of left ventricular (LV) dysfunction after MI. Age-matched female Wistar rats were treated as follows: 1) no… CONTINUE READING