Regulation of collagen pathway biology during follicle maturation in the rat ovary

@inproceedings{Shearer2007RegulationOC,
  title={Regulation of collagen pathway biology during follicle maturation in the rat ovary},
  author={Kirsty D. Shearer},
  year={2007}
}
Ovulation is a natural, recurrent injury involving sustained breakdown and remodelling of extracellular matrix (ECM) proteins, as follicles grow, ovulate and luteinise during each reproductive cycle. It is generally accepted that ovulation-associated tissue injury is the end-product of an acute inflammatory cascade driven by gonadotrophins (folliclestimulating hormone (FSH) and luteinising hormone (LH)) and inflammatory mediators that signal up-regulation of matrix metalloproteinase enzymes… CONTINUE READING

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