Regulation of coenzyme A transferase and acetoacetate decarboxylase activities in Clostridium acetobutylicum.

@article{JanatiIdrissi1988RegulationOC,
  title={Regulation of coenzyme A transferase and acetoacetate decarboxylase activities in Clostridium acetobutylicum.},
  author={R. Janati-Idrissi and A. Junelles and H. Petitdemange and R. Gay},
  journal={Annales de l'Institut Pasteur. Microbiology},
  year={1988},
  volume={139 6},
  pages={
          683-8
        }
}
The activity of two enzymes involved in acetone production in Clostridium acetobutylicum, acetoacetate decarboxylase and coenzyme A transferase, was studied under acidogenic or solventogenic conditions. Acetoacetate decarboxylase activity was low under acidogenic conditions and after pyruvate addition. Under the same conditions, coenzyme A transferase activity was high. A mutant which lacked acetoacetate decarboxylase activity but was positive for coenzyme A transferase activity was isolated.