Regulation of ciliated cell differentiation in cultures of rat tracheal epithelial cells.

@article{Clark1995RegulationOC,
  title={Regulation of ciliated cell differentiation in cultures of rat tracheal epithelial cells.},
  author={Alan B. Clark and Scott H. Randell and Paul Nettesheim and Thomas Scott Gray and B Bagnell and Lawrence E Ostrowski},
  journal={American journal of respiratory cell and molecular biology},
  year={1995},
  volume={12 3},
  pages={329-38}
}
The cellular pathway of ciliated cell differentiation and its regulation is poorly defined. To begin to understand the process of ciliated cell differentiation, we sought to identify factors regulating ciliated cell development in vitro. Rat tracheal epithelial (RTE) cells were cultured on collagen gel-coated membranes at an air-liquid interface in hormone- and growth factor-supplemented medium (complete medium [CM]). Under these conditions, RTE cells first proliferate and then differentiate… CONTINUE READING

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