Regulation of chromatin structure by histone H3S10 phosphorylation

  title={Regulation of chromatin structure by histone H3S10 phosphorylation},
  author={K. Johansen and J. Johansen},
  journal={Chromosome Research},
  • K. Johansen, J. Johansen
  • Published 2006
  • Biology, Medicine
  • Chromosome Research
  • The epigenetic phospho-serine 10 modification of histone H3 has been a puzzle due to its association with two apparently opposed chromatin states. It is found at elevated levels on the highly condensed, transcriptionally inactive mitotic chromosomes yet is also correlated with the more extended chromatin configuration of active genes, euchromatic interband regions, and activated heat shock puffs of Drosophila polytene chromosomes. In addition, phosphorylation of histone H3S10 is up-regulated on… CONTINUE READING
    169 Citations

    Figures and Topics from this paper.

    Covalent modifications of histones during mitosis and meiosis
    • 86
    H3 phosphorylation: dual role in mitosis and interphase.
    • 99
    Epigenetic Control of Cell Division
    • 8
    The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas
    • 50
    • PDF
    Modifying Chromatin by Histone Tail Clipping.
    • 8
    Quantitative proteomic analysis of histone modifications.
    • 194
    Histones and genome integrity.
    • 14
    • PDF
    Characterisation of the (H3-H4)2-tetramer and its interaction with histone chaperones
    Epigenetic virtues of chromodomains
    • 52


    Phosphorylation of histone H3 correlates with transcriptionally active loci.
    • 243
    • PDF
    Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation
    • 914
    Phosphorylation of serine 10 in histone H3, what for?
    • 421
    • PDF
    Histone H3 phosphorylation and cell division
    • 452
    • PDF
    Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin
    • 618
    Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
    • 2,649
    Phosphorylation of histone H3 during transcriptional activation depends on promoter structure.
    • 56
    • PDF
    The language of covalent histone modifications
    • 7,523
    • Highly Influential
    • PDF
    Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly
    • 1,580
    • PDF