Regulation of chemokine production in response to pro-inflammatory cytokines in first trimester decidual cells.

@article{Huang2006RegulationOC,
  title={Regulation of chemokine production in response to pro-inflammatory cytokines in first trimester decidual cells.},
  author={S Joseph Huang and Frederick Schatz and Rachael Masch and Mizanur Rahman and Lynn F Buchwalder and Tracy Niven-Fairchild and Chuan-ling Tang and Vikki M Abrahams and Graciela Krikun and Charles Joseph Lockwood},
  journal={Journal of reproductive immunology},
  year={2006},
  volume={72 1-2},
  pages={60-73}
}
OBJECTIVE Chemokines initiate the immune response by controlling leukocyte migration and lymphocyte development. Macrophage infiltration of the decidua has been implicated in the genesis of recurrent miscarriage and preeclampsia. Therefore, we determined whether cultured human decidual cells produce monocyte/macrophage-recruiting chemokines in response to a potent pro-inflammatory cytokine, interleukin-1beta (IL-1beta), and whether decidual cell-conditioned medium contains monocyte- and… CONTINUE READING
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