Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS

@article{Koizumi2005RegulationOC,
  title={Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS},
  author={Schuichi Koizumi and Kayoko Fujishita and Kazuhide Inoue},
  journal={Purinergic Signalling},
  year={2005},
  volume={1},
  pages={211 - 217}
}
It has become apparent that glial cells, especially astrocytes, not merely supportive but are integrative, being able to receive inputs, assimilate information and send instructive chemical signals to other neighboring cells including neurons. At first, the excitatory neurotransmitter glutamate was found to be a major extracellular messenger that mediates these communications because it can be released from astrocytes in a Ca2+-dependent manner, diffused, and can stimulate extra-synaptic… CONTINUE READING

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