Regulation of cell motile activity through the different induction of LPA receptors by estrogens in liver epithelial WB-F344 cells.

@article{Tanabe2012RegulationOC,
  title={Regulation of cell motile activity through the different induction of LPA receptors by estrogens in liver epithelial WB-F344 cells.},
  author={Eriko Tanabe and Ayano Shibata and Serina Inoue and Misaho Kitayoshi and Nobuyuki Fukushima and Toshifumi Tsujiuchi},
  journal={Biochemical and biophysical research communications},
  year={2012},
  volume={428 1},
  pages={
          105-9
        }
}
Lysophosphatidic acid (LPA) interacts with G protein-coupled transmembrane LPA receptors (LPA receptors; LPA(1)-LPA(6)). Recently, we demonstrated that each LPA receptor acts as a positive or negative regulator of cell migration ability. It is known that estrogens indicate a variety of biological functions, including cell motility. In the present study, to assess whether LPA signaling is involved in cell motile activity stimulated by estrogens, we measured cell motile activity and LPA receptor… CONTINUE READING
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