Regulation of cell death and survival by resveratrol: implications for cancer therapy.

@article{Fulda2012RegulationOC,
  title={Regulation of cell death and survival by resveratrol: implications for cancer therapy.},
  author={Simone Fulda},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2012},
  volume={12 8},
  pages={874-9}
}
  • Simone Fulda
  • Published 2012 in Anti-cancer agents in medicinal chemistry
Apoptosis is a critical regulatory mechanism to control tissue homeostasis. Accordingly, too little apoptosis can contribute to cancer. Natural compounds, e.g. polyphenols such as resveratrol, have emerged as promising agents for cancer chemoprevention and therapy, since they interfere with various major signaling cascades that are aberrantly regulated in cancers. For example, resveratrol can antagonize signaling events that prevent apoptosis or support cancer proliferation. Further elucidation… CONTINUE READING