Regulation of cell cycle transcription factor Swi5 by karyopherin Msn5.

Abstract

Inactivation of S. cerevisiae β-karyopherin Msn5 causes hypersensitivity to the overexpression of mitotic cyclin Clb2 and aggravates growth defects of many mutant strains in mitotic exit, suggesting a connection between Msn5 and mitotic exit. We determined that Msn5 controlled subcellular localization of the mitotic exit transcription factor Swi5, since it… (More)
DOI: 10.1016/j.bbamcr.2012.02.009

Topics

  • Presentations referencing similar topics