Regulation of cell-cell adhesion by the cadherin-catenin complex.

  • Ward Nelson
  • Published 2008 in Biochemical Society transactions


Ca(2+)-dependent cell-cell adhesion is regulated by the cadherin family of cell adhesion proteins. Cadherins form trans-interactions on opposing cell surfaces which result in weak cell-cell adhesion. Stronger cell-cell adhesion occurs by clustering of cadherins and through changes in the organization of the actin cytoskeleton. Although cadherins were… (More)
DOI: 10.1042/BST0360149


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