Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors.

@article{BotellaPava2004RegulationOC,
  title={Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors.},
  author={Patricia Botella-Pav{\'i}a and Oscar Besumbes and Michael A Phillips and Lorenzo Carretero-Paulet and Albert Boronat and Manuel Rodr{\'i}guez-Concepc{\'i}on},
  journal={The Plant journal : for cell and molecular biology},
  year={2004},
  volume={40 2},
  pages={188-99}
}
Carotenoids are isoprenoid pigments that function as photoprotectors, precursors of the hormone abscisic acid (ABA), colorants and nutraceuticals. A major problem for the metabolic engineering of high carotenoid levels in plants is the limited supply of their isoprenoid precursor geranylgeranyl diphosphate (GGPP), formed by condensation of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) units usually synthesized by the methylerythritol phosphate (MEP) pathway in plastids… CONTINUE READING

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