Regulation of cardiac myocyte cell death.

  title={Regulation of cardiac myocyte cell death.},
  author={Angela Clerk and Sharon M Cole and Timothy E. Cullingford and Joanne G Harrison and Mika Jormakka and Donna M Valks},
  journal={Pharmacology & therapeutics},
  volume={97 3},
Cardiac myocyte death, whether through necrotic or apoptotic mechanisms, is a contributing factor to many cardiac pathologies. Although necrosis and apoptosis are the widely accepted forms of cell death, they may utilize the same cell death machinery. The environment within the cell probably dictates the final outcome, producing a spectrum of response between the two extremes. This review examines the probable mechanisms involved in myocyte death. Caspases, the generally accepted executioners… CONTINUE READING