Regulation of cancer cell metabolism

  title={Regulation of cancer cell metabolism},
  author={R. Cairns and I. Harris and T. Mak},
  journal={Nature Reviews Cancer},
  • R. Cairns, I. Harris, T. Mak
  • Published 2011
  • Medicine, Biology
  • Nature Reviews Cancer
  • Interest in the topic of tumour metabolism has waxed and waned over the past century of cancer research. The early observations of Warburg and his contemporaries established that there are fundamental differences in the central metabolic pathways operating in malignant tissue. However, the initial hypotheses that were based on these observations proved inadequate to explain tumorigenesis, and the oncogene revolution pushed tumour metabolism to the margins of cancer research. In recent years… CONTINUE READING
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