Regulation of calcineurin gene expression in Schizosaccharomyces pombe. Dependence on the ste11 transcription factor.

@article{PlochockaZulinska1995RegulationOC,
  title={Regulation of calcineurin gene expression in Schizosaccharomyces pombe. Dependence on the ste11 transcription factor.},
  author={D Plochocka-Zulinska and Grethe Rasmussen and Camilla Holzmann Rasmussen},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 42},
  pages={24794-9}
}
Calmodulin and its target enzymes are important regulators of numerous cellular processes, including reversible protein phosphorylation. The calmodulin-dependent protein phosphatase (calcineurin) has been suggested to play roles in activation of T cells and in the mating response of yeast. Recently, studies have shown it to be the target of immunosuppressant drugs such as cyclosporin and FK-506. In this study, we have cloned the gene for the catalytic subunit of calcineurin, CnA, from the yeast… CONTINUE READING