Regulation of breathing and autonomic outflows by chemoreceptors.

@article{Guyenet2014RegulationOB,
  title={Regulation of breathing and autonomic outflows by chemoreceptors.},
  author={Patrice G Guyenet},
  journal={Comprehensive Physiology},
  year={2014},
  volume={4 4},
  pages={1511-62}
}
Lung ventilation fluctuates widely with behavior but arterial PCO2 remains stable. Under normal conditions, the chemoreflexes contribute to PaCO2 stability by producing small corrective cardiorespiratory adjustments mediated by lower brainstem circuits. Carotid body (CB) information reaches the respiratory pattern generator (RPG) via nucleus solitarius (NTS) glutamatergic neurons which also target rostral ventrolateral medulla (RVLM) presympathetic neurons thereby raising sympathetic nerve… CONTINUE READING
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