Regulation of bicarbonate transport across the brush border membrane of the bull-frog choroid plexus.

@article{Saito1984RegulationOB,
  title={Regulation of bicarbonate transport across the brush border membrane of the bull-frog choroid plexus.},
  author={Yoshitaka Saito and Ernest M Wright},
  journal={The Journal of physiology},
  year={1984},
  volume={350},
  pages={327-42}
}
Our previous study of the choroid plexus showed that elevation of cellular cyclic AMP stimulated HCO3 secretion into the cerebrospinal fluid (c.s.f.). To explore the mechanism of this stimulation, we have used micro-electrodes to observe the effect of phosphodiesterase inhibitors on membrane potentials, resistances and electromotive forces (e.m.f.) in the bull-frog plexus. The potential profile under control conditions was -45 mV across the apical membrane (Vvc) and -9 mV across the epithelium… CONTINUE READING