Regulation of beta-tubulin function and expression in Drosophila spermatogenesis.

  title={Regulation of beta-tubulin function and expression in Drosophila spermatogenesis.},
  author={Henry D. Hoyle and Jeffrey A. Hutchens and Franziska Turner and Elizabeth C. Raff},
  journal={Developmental genetics},
  volume={16 2},
In this study we examined two aspects of beta-tubulin function in Drosophila spermatogenesis: 1) beta-tubulin structural requirements for assembly of different categories of microtubules and 2) regulatory requirements for production of the correct tubulin protein level. In normal Drosophila spermatogenesis, the testis-specific beta 2-tubulin isoform supports multiple microtubule functions. Our previous work showed that another Drosophila isoform, beta 3, cannot support spermatogenesis, whereas… CONTINUE READING