Regulation of autophagy by amino acids and MTOR-dependent signal transduction

  title={Regulation of autophagy by amino acids and MTOR-dependent signal transduction},
  author={Alfred J. Meijer and S{\'e}verine Lorin and Edward F C Blommaart and Patrice Codogno},
  booktitle={Amino Acids},
Amino acids not only participate in intermediary metabolism but also stimulate insulin-mechanistic target of rapamycin (MTOR)-mediated signal transduction which controls the major metabolic pathways. Among these is the pathway of autophagy which takes care of the degradation of long-lived proteins and of the elimination of damaged or functionally redundant organelles. Proper functioning of this process is essential for cell survival. Dysregulation of autophagy has been implicated in the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
31 Citations
287 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 31 extracted citations


Publications referenced by this paper.
Showing 1-10 of 287 references

Similar Papers

Loading similar papers…