Regulation of autophagy by Ca2+

  title={Regulation of autophagy by Ca2+},
  author={Fang Sun and Xia Xu and Xiaohong Wang and Bei Zhang},
  booktitle={Tumor Biology},
Autophagy is an evolutionarily conserved lysosomal catabolic process used as an internal engine in response to nutrient starvation or metabolic stress. A number of protein complexes and an intricate network of stress signaling cascades impinge on the regulation of autophagy; the mammalian target of rapamycin serves as a canonical player. Ca2+, as a major intracellular second messenger, regulates multiple physiological and pathological functions. Although significant information is already well… CONTINUE READING

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