Regulation of autonomic nerve activities by central pituitary adenylate cyclase-activating polypeptide.

@article{Tanida2010RegulationOA,
  title={Regulation of autonomic nerve activities by central pituitary adenylate cyclase-activating polypeptide.},
  author={Mamoru Tanida and Norihito Shintani and Yoshiko Morita and Naohiro Tsukiyama and Michiyoshi Hatanaka and Hitoshi Hashimoto and Hajime Sawai and A. Ramesha Baba and Katsuya Nagai},
  journal={Regulatory peptides},
  year={2010},
  volume={161 1-3},
  pages={73-80}
}
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a peptidergic neurotransmitter that is expressed in high levels in nervous systems. Here, we investigated the roles of PACAP in autonomic system regulation by evaluating the changes caused in the autonomic nerve activities after injecting PACAP into the central nervous system (CNS) and examining stress-induced blood glucose changes in PACAP-deficient (PACAP-/-) mice. Renal sympathetic nerve activity (RSNA), blood pressure, and heart… CONTINUE READING
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