Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits.


BACKGROUND/AIMS Portal hypertension is characterized by a marked splanchnic hyperemia due to a reduction in mesenteric vascular resistance. Possible mediators of this decreased resistance include an increased amount of and/or responsiveness to vasodilatory substances. Previous studies have demonstrated an enhanced hypotensive effect of exogenous atrial… (More)


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