Regulation of aromatase activity of rat granulosa cells: induction of synthesis of NADPH-cytochrome P-450 reductase by FSH and dibutyryl cyclic AMP.

Abstract

Aromatase is an enzyme complex that is composed of a specific form of cytochrome P-450 and a flavoprotein, NADPH-cytochrome P-450 reductase. Aromatase activity of granulosa cells is increased markedly by follicle-stimulating hormone (FSH) and by analogs of cyclic AMP. It was the objective of the present study to investigate the effects of FSH and dibutyryl… (More)

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@article{Durham1985RegulationOA, title={Regulation of aromatase activity of rat granulosa cells: induction of synthesis of NADPH-cytochrome P-450 reductase by FSH and dibutyryl cyclic AMP.}, author={Christopher R Durham and Haibin Zhu and Bettie Sue Siler Masters and Evan R. Simpson and Carole R. Mendelson}, journal={Molecular and cellular endocrinology}, year={1985}, volume={40 2-3}, pages={211-9} }