Regulation of arachidonic acid metabolism by macrophage activation

  title={Regulation of arachidonic acid metabolism by macrophage activation},
  author={Walter Alvin Scott and Nicholas A Pawlowski and Henry W. Murray and M Andreach and Joanne Zrike and Zanvil Alexander Cohn},
  journal={The Journal of Experimental Medicine},
  pages={1148 - 1160}
Levels of zymosan-induced arachidonic acid (20:4) metabolism by peritoneal macrophages elicited with inflammatory agents and resident macrophages were similar. Thyioglycollate (THIO)-elicited macrophages represented the exception; however, the diminished metabolism by these cells was reproduced by exposing resident cells to 5 mg/ml THIO broth in vitro. In contrast, reduced prostaglandin synthesis by macrophages from mice variously treated with the immunologic agents, Corynebacterium parvum or… CONTINUE READING


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Dynamics of leukotriene C production by macrophages.J

  • C. A. Rouzer, W. A. Scott, A. L. Hamill, Z. A. Cohn
  • Exp. Med
  • 1980
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