Regulation of aquaporin mRNA expression in rat kidney by water intake.

  title={Regulation of aquaporin mRNA expression in rat kidney by water intake.},
  author={Maribel Murillo-Carretero and Anunciaci{\'o}n Ana Ilundain and Miriam Echevarr{\'i}a},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={10 4},
Three aquaporins (AQP) are present in the membrane of the principal collecting duct cells. On the apical side, the levels of AQP2 protein are increased in response to both arginine vasopressin and water deprivation. However, whether this change parallels changes in the abundance of AQP3 and AQP4 in the basolateral membrane is less well known. This study evaluates the effect of either dehydration or water loading on the rat kidney mRNA expression of AQP2, AQP3, and AQP4. Poly(A+)RNA was prepared… CONTINUE READING


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