Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis.


Ulcerative colitis is an inflammatory bowel disease involving the colon resulting in bloody diarrhea and increased risk of colorectal cancer in certain patient subgroups. Increased apoptosis in the epithelial cell layer causes increased permeability, especially during flares; this leads to translocation of luminal pathogens resulting in a continued… (More)
DOI: 10.3109/00365521.2016.1101245


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