Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters.

Abstract

MicroRNAs (miRNAs) modulate complex physiological and pathological processes by repressing expression of multiple components of cellular regulatory networks. Here we demonstrate that miRNAs encoded by the miR-23∼27∼24 gene clusters are enriched in endothelial cells and highly vascularized tissues. Inhibition of miR-23 and miR-27 function by locked nucleic… (More)
DOI: 10.1073/pnas.1105254108

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