Regulation of amniotic fluid volume: mathematical model based on intramembranous transport mechanisms.

@article{Brace2014RegulationOA,
  title={Regulation of amniotic fluid volume: mathematical model based on intramembranous transport mechanisms.},
  author={Robert A. Brace and Debra F. Anderson and Cecilia Y. Cheung},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2014},
  volume={307 10},
  pages={R1260-73}
}
Experimentation in late-gestation fetal sheep has suggested that regulation of amniotic fluid (AF) volume occurs primarily by modulating the rate of intramembranous transport of water and solutes across the amnion into underlying fetal blood vessels. In order to gain insight into intramembranous transport mechanisms, we developed a computer model that allows simulation of experimentally measured changes in AF volume and composition over time. The model included fetal urine excretion and lung… CONTINUE READING
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