Regulation of adipose tissue metabolism in cancer cachexia.

  title={Regulation of adipose tissue metabolism in cancer cachexia.},
  author={C. Si. Bing and Paul Trayhurn},
  journal={Current opinion in clinical nutrition and metabolic care},
  volume={11 3},
PURPOSE OF REVIEW Body-fat depletion is a hallmark of cancer cachexia, a complex clinical syndrome associated with increased morbidity and mortality. Understanding the fat-loss disorder in cachexia is essential for the development of better treatments for the syndrome. This review presents recent studies focusing on the mechanisms of adipose atrophy in cancer cachexia, particularly the potential mediators. RECENT FINDINGS Fat loss cannot be explained by poor appetite alone, and may also… CONTINUE READING


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