Regulation of adipose differentiation by fructose and GluT5.

  title={Regulation of adipose differentiation by fructose and GluT5.},
  author={Li Du and Anthony Patrick Heaney},
  journal={Molecular endocrinology},
  volume={26 10},
Adipose tissue is an important metabolic organ that is crucial for whole-body insulin sensitivity and energy homeostasis. Highly refined fructose intake increases visceral adiposity although the mechanism(s) remain unclear. Differentiation of preadipocytes to mature adipocytes is a highly regulated process that is associated with characteristic sequential changes in adipocyte gene expression. We demonstrate that fructose treatment of murine 3T3-L1 cells incubated in standard differentiation… CONTINUE READING
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