Regulation of adipocyte lipolysis.

  title={Regulation of adipocyte lipolysis.},
  author={G. Fr{\"u}hbeck and L. M{\'e}ndez-Gim{\'e}nez and Jos{\'e}-Antonio Fern{\'a}ndez-Formoso and S. Fern{\'a}ndez and A. Rodr{\'i}guez},
  journal={Nutrition research reviews},
  volume={27 1},
  • G. Frühbeck, L. Méndez-Giménez, +2 authors A. Rodríguez
  • Published 2014
  • Biology, Medicine
  • Nutrition research reviews
  • In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting conditions or times of elevated energy demands is tightly regulated by neuroendocrine signals, resulting in the activation of lipolytic enzymes. Among the classic regulators of lipolysis, adrenergic stimulation and the insulin-mediated control of lipid mobilisation are the best known. Initially, hormone-sensitive lipase (HSL) was thought to be the rate-limiting enzyme of the first lipolytic step, while we now… CONTINUE READING
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