Regulation of acyl-coenzyme A: cholesterol acyltransferase 2 expression by saturated fatty acids.

@article{Zhuqin2010RegulationOA,
  title={Regulation of acyl-coenzyme A: cholesterol acyltransferase 2 expression by saturated fatty acids.},
  author={Zhang Zhu-qin and Chen Hou-zao and Yang Rui-feng and Zhang Ran and Jia Yu-yan and Xi Yang and Liu De-pei and Liang Chih-chuan},
  journal={Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih},
  year={2010},
  volume={25 4},
  pages={
          222-7
        }
}
OBJECTIVE To verify the regulation of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT 2), which is associated with cholesterol metabolism, by saturated fatty acids (SFAs). METHODS Palmitic acid (PA), the most abundant saturated fatty acid in plasma, and oleic acid (OA), a widely distributed unsaturated fatty acid, were used to treat hepatic cells HepG2, HuH7, and mouse primary hepatocytes. In addition, PA at different concentrations and PA treatment at different durations were applied in… CONTINUE READING
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