Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy.

Abstract

RATIONALE Histone deacetylases (HDACs) are closely involved in cardiac reprogramming. Although the functional roles of class I and class IIa HDACs are well established, the significance of interclass crosstalk in the development of cardiac hypertrophy remains unclear. OBJECTIVE Recently, we suggested that casein kinase 2α1-dependent phosphorylation of… (More)
DOI: 10.1161/CIRCRESAHA.114.303429

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