Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma.

@article{Kapanadze2013RegulationOA,
  title={Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma.},
  author={Tamar Kapanadze and Jaba Gamrekelashvili and Chi Ma and Carmen Chan and Fei Zhao and Stephen Hewitt and Lars Zender and Veena Kapoor and Dean W. Felsher and Michael P. Manns and Firouzeh Korangy and Tim F Greten},
  journal={Journal of hepatology},
  year={2013},
  volume={59 5},
  pages={1007-13}
}
BACKGROUND & AIMS Myeloid derived suppressor cells (MDSC) are immature myeloid cells with immunosuppressive activity. They accumulate in tumor-bearing mice and humans with different types of cancer, including hepatocellular carcinoma (HCC). The aim of this study was to examine the biology of MDSC in murine HCC models and to identify a model, which mimics… CONTINUE READING