Regulation of a truncated isoform of AMP-activated protein kinase α (AMPKα) in response to hypoxia in the muscle of Pacific oyster Crassostrea gigas

@article{Guvlou2013RegulationOA,
  title={Regulation of a truncated isoform of AMP-activated protein kinase α (AMPKα) in response to hypoxia in the muscle of Pacific oyster Crassostrea gigas},
  author={Eric Gu{\'e}v{\'e}lou and Arnaud Huvet and Rossana Sussarellu and Massimo Milan and Ximing Guo and Lin Li and Guofan Zhang and Virgile Quillien and J. -Y. Daniel and C. Quere and Pierre Boudry and Charlotte Corporeau},
  journal={Journal of Comparative Physiology B},
  year={2013},
  volume={183},
  pages={597-611}
}
AMP-activated protein kinase α (AMPKα) is a key regulator of energy balance in many model species during hypoxia. In a marine bivalve, the Pacific oyster Crassostrea gigas, we analyzed the protein content of adductor muscle in response to hypoxia during 6 h. In both smooth and striated muscles, the amount of full-length AMP-activated protein kinase α (AMPKα) remained unchanged during hypoxia. However, hypoxia induced a rapid and muscle-specific response concerning truncated isoforms of AMPK… CONTINUE READING

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